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Multi-Sequence Alignment Algorithm Design
Optimize an algorithm for aligning protein sequences with high computational efficiency.
📝 Prompt-Inhalt
Propose an algorithm for Multiple Sequence Alignment (MSA) of protein sequences that improves upon the progressive alignment method (like ClustalW) by incorporating consistency-based scoring. Discuss the computational complexity of your approach and how it handles gaps and mutations in conserved regions differently from standard dynamic programming approaches.